Combination antibiotic therapy for multidrug-resistant Gram-negative bacteria
نویسندگان
چکیده
منابع مشابه
Combination antibiotic therapy for multidrug-resistant Gram-negative bacteria
Combination antibiotic therapy for Gram-negative sepsis is controversial. The present review provides a brief summary of the existing knowledge on combination therapy for severe infections with multidrug-resistant Pseudomonas spp., Acinetobacter spp., and Enterobacteriaceae. Empirical combination antibiotic therapy is recommended for severe sepsis and septic shock to reduce mortality related to...
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Carbapenem-resistant Gram-negative bacteria (CR-GNB) represent an increasing hazard in healthcare settings. A central question concerning the treatment of invasive infections caused by CR-GNB involves the use of combination therapy. Potential advantages of combination therapy include improved efficacy due to synergy, while the disadvantages include adverse events and increased antibiotic use wi...
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There are 3 main groups of multiple resistant Gram-negative bacteria: Enterobacteriaceae with ESBL or AmpC enzymes – Escherichia coli, Klebsiella spp., Enterobacter cloacae, Citrobacter freundii, Morganella morganii, Serratia marcescens Acinetobacter spp. – resistant to aminoglycoside antibiotics as well as occasionally carbapenems and Colistin Pseudomonas spp. – resistant to combinations...
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OBJECTIVE a resistance of hospital-acquired bacteria to multiple antibiotics is a major concern worldwide. The objective of this study was to investigate multidrugresistant (MDR) bacteria, clinical specimens, origin of specimen and trends, and correlate these with bacterial sensitivity and consumption of antimicrobials. METHODS 9,416 bacteria of nosocomial origin were evaluated in a tertiary ...
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In the past years infections caused by multidrug-resistant Gram-negative bacteria have dramatically increased in all parts of the world. This consensus paper is based on presentations, subsequent discussions and an appraisal of current literature by a panel of international experts invited by the Rudolf Schülke Stiftung, Hamburg. It deals with the epidemiology and the inherent properties of Gra...
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ژورنال
عنوان ژورنال: Upsala Journal of Medical Sciences
سال: 2014
ISSN: 0300-9734,2000-1967
DOI: 10.3109/03009734.2014.899279